Status:

COMPLETED

Hepatitis B Challenge Dose in Adults (V232-059-10)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Hepatitis B

Eligibility:

All Genders

50+ years

Phase:

PHASE3

Brief Summary

The purpose of this trial is to describe the Seroprotection Rate (SPR) at least 2 years following completion of a primary series with a hepatitis B vaccine (Base Study V232-059, NCT00440531) and 1 mon...

Eligibility Criteria

Inclusion

  • In general good health based on a medical history.
  • Received 3 doses of an Hepatitis B vaccine in Base Study V232-059, NCT00440531 at least 2 years prior to enrollment in this study.

Exclusion

  • Known history of previous Hepatitis B infection.
  • History of vaccination with any Hepatitis B vaccine within the last 2 years.
  • History of febrile illness.
  • Known or suspected hypersensitivity to any component of HBVaxPro.
  • Receipt of medication / vaccine that may interfere with study assessments.
  • Known or suspected immune impairment.
  • Pregnant women and nursing mothers.

Key Trial Info

Start Date :

November 30 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 12 2011

Estimated Enrollment :

204 Patients enrolled

Trial Details

Trial ID

NCT01251276

Start Date

November 30 2010

End Date

April 12 2011

Last Update

September 13 2022

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