Status:
COMPLETED
Household Influenza Transmission Study
Lead Sponsor:
Centers for Disease Control and Prevention
Collaborating Sponsors:
Ministry of Health, Thailand
Armed Forces Research Institute of Medical Sciences, Thailand
Conditions:
Influenza
Eligibility:
All Genders
1-15 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether nonpharmaceutical interventions (i.e., handwashing and masks) reduce secondary transmission of influenza in households.
Detailed Description
HITS is a multi-year project that will prospectively identify laboratory-confirmed influenza infected children. Secondary influenza infection will then be examined among members of the child's househo...
Eligibility Criteria
Inclusion
- Child, 1 month through 15 years of age
- Resident of Bangkok Metropolitan Area
- Outpatient of Queen Sirikit National Institute of Child Health Children's
- Hospital seen during HITS' active study period
- Positive influenza rapid test result from patient presenting with influenza-like illness
- In addition to the index case, consent must be obtained from at least 2 household members ≥1 month of age who plan to sleep inside the house for a period of at least 21 days from the time of enrollment
Exclusion
- Illness onset 48 hours or more before presentation and influenza testing at Queen Sirikit National Institute of Child Health Children's Hospital
- Treatment with influenza antiviral medications since it may decrease secondary attack rate
- Children who are at high risk for severe influenza disease (e.g., chronic lung disease, renal disease, chemotherapy for cancer, long-term aspirin therapy)
- A history of influenza-like illness in another household member that precedes the index case by 7 days or less will lead to exclusion of the household because the source of influenza infection for secondary cases is uncertain.
- Receipt of influenza vaccine by any household member during the preceding 12 months.
- Prior participation in HITS.
Key Trial Info
Start Date :
April 9 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2013
Estimated Enrollment :
2920 Patients enrolled
Trial Details
Trial ID
NCT01251679
Start Date
April 9 2008
End Date
November 1 2013
Last Update
September 19 2024
Active Locations (1)
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1
Queen Sirikit National Institute of Child Health
Ratchathewi, Bangkok, Thailand, 10400