Status:
COMPLETED
Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies
Lead Sponsor:
Kaiser Permanente
Collaborating Sponsors:
Kaiser Foundation Hospitals, Center for Health Research
Johns Hopkins University
Conditions:
Diabetes Mellitus
Cardiovascular Disease
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
The purpose of this randomized clinical trial is to determine whether two low-intensity, technology based interventions, when compared to each other and to usual care, improve adherence to selected me...
Detailed Description
The frequent failure of patients to adhere to long-term medication regimens remains the single greatest challenge for chronic-disease management. Many studies have linked medication non-adherence to t...
Eligibility Criteria
Inclusion
- Aged 40 years or older as of time of randomization.
- Flagged in KP's databases as having either diabetes or atherosclerotic cardiovascular disease(defined as coronary artery disease, peripheral vascular disease, or a history of atherosclerotic stroke) at the time of randomization
- At least one dispensing of an ACEI, ARB, or statin from a Kaiser Permanente (KP) outpatient pharmacy during the baseline year.
- Suboptimal adherence ((MPR\<0.9) to either statins or ACEI/ARBs during the baseline year
- Continuous membership in KP for the 12 months prior to randomization.
- Qualified for an intervention call at the time of randomization.
Exclusion
- Evidence in the electronic medical record (EMR) of allergy or intolerance to statins or ACE inhibitors/ARBs
- medical conditions that would contraindicate use of statins or ACEI/ARBs
- Absence of either a phone number or mailing address in the EMR
- for Kaiser Permanente Hawaii, clinics whose patients tend to fill prescriptions primarily at non-KP pharmacies
- on Kaiser Permanente's "do not contact" list or in other research studies that could add undue burden
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2013
Estimated Enrollment :
21752 Patients enrolled
Trial Details
Trial ID
NCT01251757
Start Date
August 1 2011
End Date
August 1 2013
Last Update
March 13 2017
Active Locations (3)
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1
Center for Health Research, Kaiser Permanente Southeast
Atlanta, Georgia, United States, 30305
2
Center for Health Research, Kaiser Permanente Hawaii
Honolulu, Hawaii, United States, 96817
3
Center for Health Research, Kaiser Permanente Northwest
Portland, Oregon, United States, 97227