Status:
COMPLETED
The Effect of Physical Properties of Lipid Emulsions on Gastrointestinal Function
Lead Sponsor:
University of Zurich
Conditions:
Healthy Controls
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
This study will investigate the effects of particle size of different triglyceride emulsions as well as the dynamics of intragastric structure formation and breakdown of the emulsions on GI function, ...
Detailed Description
The mechanisms by which food structure impacts on lipid digestion and the subsequent metabolic processes, including the impact on satiety and satiation, are relatively unexplored, but may have great c...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Body mass index (BMI): 18.5-24.9 kg/m2,
- Able to communicate well with the investigators
- Provide written consent
- Exclusion criteria:
- General exclusion criteria:
- Psychiatric (DSM IV) disorders limiting the ability to comply with study requirements
- Epilepsy
- Presence of metallic implants, devices or metallic foreign bodies
- Use of medications influencing upper GI motility within one week of the study (i.e. calcium channel blockers, prokinetic drugs, macrolide antibiotics)
- Evidence of current drug or alcohol abuse
- Previous history of gastrointestinal disease or surgery of the upper GI tract except appendicectomy or hernia repair
- Pregnancy and lactation period
Exclusion
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT01253005
Start Date
January 1 2011
End Date
November 1 2012
Last Update
November 14 2012
Active Locations (1)
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1
University Hospital Zurich, Gastroenterology and Hepatology
Zurich, Canton of Zurich, Switzerland, 8091