Status:

COMPLETED

A Study for Japanese Participants With Rheumatoid Arthritis (RA)

Lead Sponsor:

Eli Lilly and Company

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

20-75 years

Phase:

PHASE1

Brief Summary

This study will evaluate the safety and tolerability of multiple doses of LY2127399 (tabalumab) in Japanese participants with RA. The study consists of a 20-week treatment period. All participants wil...

Eligibility Criteria

Inclusion

  • Have given written informed consent
  • Women must not be pregnant, breastfeeding or be at risk to become pregnant during study participation
  • Diagnosis of RA
  • Active RA
  • Current, regular use of Methotrexate, at a stable dose
  • Body weight between 40 and 105 kilograms (kg), inclusive

Exclusion

  • Use of excluded medications (reviewed by study doctor)
  • Have medical findings which, in the opinion of the study doctor, put participant at an unacceptable risk for participation in the study
  • Have had recent or ongoing infection which, in the opinion of the study doctor put participant at an unacceptable risk for participation
  • Evidence of tuberculosis
  • Have systemic inflammatory condition other than RA

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT01253226

Start Date

September 1 2009

End Date

August 1 2011

Last Update

October 23 2018

Active Locations (10)

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Page 1 of 3 (10 locations)

1

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Aichi, Japan

2

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Chiba, Japan

3

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Fukui, Japan

4

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Gunma, Japan