Status:
COMPLETED
A Drug-Drug Interaction Study Between AZD1981 and Pravastatin to Study the Effect of AZD1981 on the Kinetics of Pravastatin
Lead Sponsor:
AstraZeneca
Conditions:
Drug Interaction
Eligibility:
MALE
18-55 years
Phase:
PHASE1
Brief Summary
The primary purpose of this study is to determine whether the treatment with AZD1981 will affect the pharmacokinetics of pravastatin.
Eligibility Criteria
Inclusion
- Healthy male volunteers aged 18 to 55, inclusive
- Have a body mass index between 19 and 30 kg/m2 and weight at least 50 kg and no more than 100 kg, inclusive
- Be a non-smoker or ex-smoker who has stopped smoking for \>6 months prior to screening
- Volunteers must be willing to use barrier methods of contraception during study and 3 months after the end of their participation in the study
Exclusion
- Any clinically significant disease or disorder
- Any clinically relevant abnormal findings in physical examination
Key Trial Info
Start Date :
February 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2011
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01254461
Start Date
February 1 2011
End Date
April 1 2011
Last Update
April 29 2011
Active Locations (1)
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1
Research Site
Uppsala, Sweden