Status:
COMPLETED
Changes in Ciliary Body Thickness in Patients With Diabetic Macular Edema After Vitrectomy
Lead Sponsor:
Seoul National University Hospital
Collaborating Sponsors:
Ministry of Health & Welfare, Korea
Conditions:
Diabetic Macular Edema
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether ciliary body thickness increased in the presence of diabetic macular edema and whether it changed after pars plana vitrectomy.
Detailed Description
A diabetic macular edema group consisted of diabetic patients who underwent PPV for diffuse diabetic macular edema. A epiretinal membrane group, a surgical control group, consisted of non-diabetic pat...
Eligibility Criteria
Inclusion
- Inclusion Criteria for diabetic macular edema group:
- Diabetic macular edema with preoperative central macular thickness \> 300 μm on optical coherence tomography
- Macular edema that was not associated with an epiretinal membrane or traction membrane
- No combined traction retinal detachment or vitreous hemorrhage
- No signs of ocular inflammatory disease on preoperative examination
- Phakic eye
- An axial length between 22.0 mm and 25.0 mm
- Exclusion Criteria for diabetic macular edema group:
- Patients with uveitis, inflammatory connective tissue disorders or a history of previous ocular surgery
- Long-term application of topical medication, a history of intravitreal steroid or anti-VEGF injection within 3 months before vitrectomy
- Inclusion Criteria for epiretinal membrane group:
- Non-diabetic patients with an epiretinal membrane who were scheduled for vitrectomy
- No ocular or systemic disease other than epiretinal membrane
- Inclusion Criteria for healthy group:
- No diabetes
- No ocular disease other than cataract
Exclusion
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT01259609
Start Date
September 1 2008
End Date
May 1 2010
Last Update
December 14 2010
Active Locations (1)
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1
Department of Ophthalmology, Seoul National University Hospital
Seoul, South Korea, 110-744