Status:

UNKNOWN

Antioxidant Supplements in the Reversal of Schistosomal Peri-portal Fibrosis

Lead Sponsor:

Addis Ababa University

Collaborating Sponsors:

Ullevaal University Hospital

University of Oslo

Conditions:

Schistosomiasis

Liver Fibrosis

Eligibility:

All Genders

5-60 years

Phase:

NA

Brief Summary

Liver fibrosis is the most serious complication of schistosomiasis mansoni. However only limited proportion of subjects with infection develop this pathology and there is limited knowledge on risk fac...

Detailed Description

Schistosomiasis is the second leading parasitic disease worldwide, after malaria. Liver fibrosis is the most serious complication of schistosomiasis mansoni which can lead to reduced work capacity and...

Eligibility Criteria

Inclusion

  • Subjects with schistosomal periportal fibrosis will be eligible for the study

Exclusion

  • Subjects with acute malaria, tuberculosis or other chronic diseases such as diabetes mellitus, cardiovascular disease or cancer will be excluded from the study.

Key Trial Info

Start Date :

January 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2015

Estimated Enrollment :

414 Patients enrolled

Trial Details

Trial ID

NCT01260012

Start Date

January 1 2010

End Date

December 1 2015

Last Update

December 15 2010

Active Locations (1)

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Aklilu Lemma Institute of Pathobiology, Addis Ababa University

Addis Ababa, Addis Ababa, Ethiopia, 1176