Status:
COMPLETED
Effect of Pharmacological Anti-lipolysis on FFA and VLDL-TG Metabolism Before and During Exercise
Lead Sponsor:
University of Aarhus
Conditions:
Diabetes
Obesity
Eligibility:
MALE
18-55 years
Phase:
NA
Brief Summary
This study will investigate free fatty acid and VLDL-TG metabolism before and during exercise with and without pharmacological antilipolysis by the niacin antagonist Acipimox. Main focuses will be VLD...
Detailed Description
Insulin resistance in liver and skeletal muscle is of central pathogenic significance in the development of type 2 diabetes. The molecular connections are unresolved but high levels of free fatty acid...
Eligibility Criteria
Inclusion
- \- healthy, untrained males
Exclusion
- medication
- history of malignancy, alcohol abuse or drug abuse
- participation in isotope trials in the last 6 months
Key Trial Info
Start Date :
April 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2012
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT01260376
Start Date
April 1 2011
End Date
September 1 2012
Last Update
September 18 2012
Active Locations (2)
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1
University Hospital of Aarhus, Norrebrogade
Aarhus, Aarhus, Denmark, 8000
2
University Hospital of Aarhus, Norrebrogade
Aarhus, Aarhus, Denmark, 8