Status:

COMPLETED

A Safety and Efficacy Study of SB1518 for the Treatment of Advanced Lymphoid Malignancies

Lead Sponsor:

S*BIO

Conditions:

Hodgkin Lymphoma

Mantle Cell Lymphoma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This is a Phase 2 study to assess the efficacy of SB1518 in the treatment of patients with advanced lymphoid malignancies including Hodgkin Lymphoma, Mantle Cell Lymphoma and Indolent Lymphoma (follic...

Eligibility Criteria

Inclusion

  • Patients with histologically documented diagnosis of one of the following lymphoid malignancies:
  • Hodgkin Lymphoma;
  • Mantle Cell Lymphoma;
  • Indolent Lymphoma (including follicular lymphoma, lymphoplasmacytic lymphoma, marginal zone lymphoma and small lymphocytic lymphoma);
  • Patients must have received at least one prior treatment regimen; patients with Hodgkin Lymphoma must have received an autologous stem cell transplant, refused or been deemed ineligible for stem cell transplant;
  • Able to understand and willing to sign the informed consent form.

Exclusion

  • Any histology other than Hodgkin Lymphoma, Mantle Cell Lymphoma or Indolent Lymphoma;
  • History of or active Central Nervous System (CNS) malignancy;
  • Active graft-versus-host disease (GVHD);

Key Trial Info

Start Date :

December 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2012

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT01263899

Start Date

December 1 2010

End Date

February 1 2012

Last Update

April 20 2012

Active Locations (5)

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Page 1 of 2 (5 locations)

1

University of Nebraska Medical Center

Omaha, Nebraska, United States, 68198

2

Weill Medical College of Cornell

New York, New York, United States, 10021

3

University of Rochester James P. Wilmot Cancer Center

Rochester, New York, United States, 14642

4

MD Anderson Cancer Canter

Houston, Texas, United States, 77030