Status:
COMPLETED
The Comparison of Energy in Take and Body Weight EXERCISE
Lead Sponsor:
Pennington Biomedical Research Center
Conditions:
Exercise
Energy
Eligibility:
All Genders
18-65 years
Brief Summary
This study will compare the effect of two doses of exercise on energy intake and body weight. The comparison will be between three groups; two exercise groups and a control group. The exercise groups ...
Detailed Description
The purpose of the E-MECHANIC Trial is to test the effect of two doses of exercise on energy intake, body weight, body composition, activity levels, and metabolic rate. The exercise doses will reflect...
Eligibility Criteria
Inclusion
- Male or female 18 - 65 years old, inclusive
- Not exercising \> 20 minutes on \> 3 days/wk and taking \< 8000 steps/d over one week measured with step counters.
- BMI \> 25 kg/m2 and \< 40 kg/m2
Exclusion
- • Current consumption of more than 14 alcoholic drinks per week
- Plan to move out of the study area within the next 6 months or plan to be out of the study area for more than 4 weeks in the next 6 months
- Have another member of household participating in the study
- Residence too far from Pennington
- A past history and/or physical examination or laboratory findings of the following medical conditions:
- Table 1. Exclusion Criteria
- Cardiovascular disease (CVD) or disorders Potential participants with a history of CVD
- Blood Pressure Potential participants who are on a stable dose of antihypertensive medication, with the exception of beta-blockers, and whose blood pressure is controlled will be eligible for enrollment.
- Diabetes Potential participants with a previous diagnosis of diabetes (Type 1 or 2) or a fasting plasma glucose \>125 mg/dl will be excluded from the study.
- Blood lipids Potential participants whose LDL-C 190 mg/dl or TG levels 300 mg/dl will be referred to their physician.
- Hematologic disorders Participants diagnosed with hematologic disorders, including anemias, bleeding disorders, chronic thrombotic disorders, or hypercoagulable states, will not be allowed into the study.
- Recent blood donation or blood loss Blood donation or blood loss from surgery or trauma during the 6 weeks before the baseline evaluation
- Weight loss-20 or more kilograms in the past year Other exclusions.
- Hospitalization for mental illness within the past 5 years or currently undergoing treatment for severe mental illness. Plans to be out of the city more than 4 weeks over the next 6 months
- Other significant medical conditions Including but not limited to chronic or recurrent respiratory, gastrointestinal, neuromuscular, neurological, or psychiatric conditions. Musculoskeletal problems interfering with exercise.
- Autoimmune or collagen vascular diseases. Immunodeficiency diseases or a positive HIV test. Malignancies in the past 5 years, with the exception of non-melanoma skin cancer therapeutically controlled. Any other medical condition or disease that is life-threatening or that can interfere with or be aggravated by exercise
Key Trial Info
Start Date :
December 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
198 Patients enrolled
Trial Details
Trial ID
NCT01264406
Start Date
December 1 2010
End Date
December 1 2015
Last Update
January 7 2025
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808