Status:
COMPLETED
Stroke Adverse Outcome is Associated With Nosocomial Infections: PCTus- Guided Antibacterial Therapy in Severe Ischemic Stroke Patients (STRAWINSKI)
Lead Sponsor:
Charite University, Berlin, Germany
Collaborating Sponsors:
Brahms AG
NeuroCure Clinical Research Center, Charite, Berlin
Conditions:
Ischemic Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Development of stroke associated pneumonia (SAP) has a detrimental effect on stroke outcome. Biomarker-guided antibiotic treatment of patients at high risk for pneumonia may help to improve stroke out...
Eligibility Criteria
Inclusion
- age ≥18 years
- stroke onset within the last 40 hours before randomisation
- clinical diagnosis of a severe (NIHSS \> 9), non-lacunar stroke in the middle cerebral artery territory
- consent given by the patient or by his/her legitimate representative where patients are incapable of giving consent themselves
Exclusion
- CT evidence of an intracerebral haemorrhage or a lacunar infarct as the probable cause of the current illness
- Antibiotic use within the last 10 days
- Suspected life expectancy of \< 3 months
- Participation in other interventional trials (on pharmaceuticals or medical devices)
- Pregnancy, lactation
- Pre-stroke mRS score ≥ 4
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT01264549
Start Date
December 1 2010
End Date
October 1 2014
Last Update
January 4 2022
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Charite University (Center for Stroke Research Berlin CSB & NeuroCure Clinical Research Center NCRC)
Berlin, Germany
2
Unfallkrankenhaus Berlin Neurologie
Berlin, Germany
3
Vivantes Auguste Viktoria Klinikum Neurologie
Berlin, Germany
4
Vivantes Neukölln Neurologie
Berlin, Germany