Status:

COMPLETED

Cognitive Behavioral Aggression Treatment

Lead Sponsor:

Temple University

Conditions:

Aggression

Eligibility:

All Genders

18-55 years

Phase:

PHASE2

Brief Summary

Aggressive behavior is a leading worldwide public health problem. Despite this, relatively little is known about how to best treat individuals who are highly angry and aggressive. A rich literature su...

Eligibility Criteria

Inclusion

  • Three or more acts of physical aggression (assault / property destruction) in past six months
  • Aggression related distress and/or impairment
  • Meets Criteria for Intermittent Explosive Disorder

Exclusion

  • Life History of DSM-IV Axis Bipolar disorder, Schizophrenia, Delusional disorder, Organic disorder, or Mental Retardation
  • Current DSM-IV Major Depressive Episode, Alcohol Dependence or other Drug Dependence
  • Current (past month) psychotropic medication use
  • Current severe suicidal or homicidal ideation necessitating immediate medical intervention
  • Current pregnancy or nursing, or existence of any medical condition that would deem the subject ineligible to undergo an fMRI (e.g., metal pins)
  • Two consecutive positive Expired Breathalyzer Alcohol or Urine Drug toxicological screens
  • Unable or unwilling to cooperate with study protocol (e.g., keep appointments, complete rating forms, read and understand informed consent).

Key Trial Info

Start Date :

May 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2016

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT01264900

Start Date

May 1 2010

End Date

February 1 2016

Last Update

March 4 2016

Active Locations (1)

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1

Temple University

Philadelphia, Pennsylvania, United States, 19122