Status:

COMPLETED

Effects of Iron on Exercise Capacity During Hypoxia

Lead Sponsor:

University of Oxford

Conditions:

Healthy Volunteers

Eligibility:

All Genders

18-60 years

Phase:

PHASE1

Brief Summary

During alveolar hypoxia, for example at high altitude or in patients with respiratory disease, there is evidence to suggest that hypoxia-induced pulmonary hypertension might limit exercise performance...

Eligibility Criteria

Inclusion

  • Age between 18 and 60 years
  • Sea level natives with no recent exposure to high altitude
  • Baseline iron indices within the normal range
  • Detectable tricuspid regurgitation on echocardiography

Exclusion

  • Significant cardiorespiratory disease
  • Known susceptibility to high altitude-related illness
  • Taking medications or iron supplementation
  • Pregnancy

Key Trial Info

Start Date :

November 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2015

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT01265108

Start Date

November 1 2010

End Date

April 1 2015

Last Update

July 29 2015

Active Locations (1)

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1

Department of Physiology, Anatomy & Genetics, University of Oxford

Oxford, United Kingdom, OX1 3PT