Status:
COMPLETED
To Investigate the Effects of AZD1981 on the QT Interval
Lead Sponsor:
AstraZeneca
Conditions:
Asthma
Eligibility:
MALE
18-55 years
Phase:
PHASE1
Brief Summary
The purpose of this research study is to evaluate the effect of AZD1981 on the electrical activity of the heart, in particular when the heart muscle is relaxed during a heart beat cycle. The effect of...
Eligibility Criteria
Inclusion
- Healthy male volunteers aged 18 to 55 years (inclusive)
- Subjects must be willing to use barrier methods of contraception during study and for 3 months after last dosing.
- Be a non-smoker or ex-smoker who has stopped smoking for \>6 months
Exclusion
- Any clinically significant disease or disorder (eg, cardiovascular, pulmonary, gastrointestinal, liver, renal, neurological, musculoskeletal, endocrine, metabolic, malignant, psychiatric, major physical impairment)
- History of additional risk factors for Torsade de Pointes (eg, heart failure, hypokalemia, personal or family history of arrhythmia or long QT syndrome)
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2011
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT01265641
Start Date
January 1 2011
End Date
April 1 2011
Last Update
June 28 2011
Active Locations (1)
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1
Researche Site
London, UK, United Kingdom