Status:

UNKNOWN

Heartsbreath Test for Heart Transplant Rejection

Lead Sponsor:

Menssana Research, Inc.

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Heart Transplant Rejection

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to demonstrate and validate a breath test for detection of biomarkers of heart transplant rejection (Grade 2R heart transplant).

Detailed Description

This is a 36 month multi-center, open label, unblinded and blinded study on subjects have had a heart transplant within the previous 12 months and are scheduled to undergo an endomyocardial biopsy. Th...

Eligibility Criteria

Inclusion

  • Subject is willing and able to cooperate with study, understand the scope of the study, and gives signed informed consent to participate.
  • Subject is the recipient of a heart transplant within the previous 12 months
  • Subject is scheduled for a routine endomyocardial biopsy
  • Subject is 18 years or older

Exclusion

  • Evidence of acute intercurrent disease other than rejection reaction

Key Trial Info

Start Date :

December 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2016

Estimated Enrollment :

1200 Patients enrolled

Trial Details

Trial ID

NCT01397812

Start Date

December 1 2010

End Date

September 1 2016

Last Update

April 7 2015

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Cedars-Sinai Medical Center

Beverly Hills, California, United States, 90211

2

Stanford University School of Medicine

Stanford, California, United States, 94305-5406

3

Newark Beth Israel Medical Center

Newark, New Jersey, United States, 07112

4

Columbia Presbyterian Medical Center

New York, New York, United States, 10032