Status:
UNKNOWN
Contrast Medium Volume and Contrast-induced Nephropathy After Percutaneous Coronary Intervention
Lead Sponsor:
Guangdong Provincial People's Hospital
Collaborating Sponsors:
Hainan People's Hospital
Guangdong Medical College
Conditions:
Contrast Induced Nephropathy
Eligibility:
All Genders
21+ years
Brief Summary
To investigate the predictive value of the contrast media volume to creatinine clearance (V/CrCl) ratio for the risk of contrast-induced nephropathy (CIN) (i.e., within 48-72 h) and to determine a rel...
Detailed Description
contrast media volume to creatinine clearance (V/CrCl) ratios were obtained from consecutive consenting patients after unselective PCI. Receiver-operator characteristic (ROC) curves were used to ident...
Eligibility Criteria
Inclusion
- patients who agreed to stay in the hospital for 2-3 days after percutaneous coronary intervention
- provided written informed consent
- Creatinine Clearance:15-60ml/min
Exclusion
- pregnancy
- lactation
- intravascular administration of an contrast medium within the previous seven days
- treatment with metformin
- aminoglycosides
- N-acetylcysteine (NAC)
- nonsteroidal anti-inflammatory drugs within the previous 48 h
- intake of nephrotoxic drugs within the previous seven days
- history of serious reactions to contrast mediums
- severe concomitant disease
- renal transplantation , or end-stage renal disease necessitating dialysis patients who died during percutaneous coronary intervention
Key Trial Info
Start Date :
January 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2012
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT01399203
Start Date
January 1 2010
End Date
January 1 2012
Last Update
August 3 2011
Active Locations (1)
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1
Ning Tan
Guangzhou, Guangdong, China, 510100