Status:
COMPLETED
Agricultural Health Study Follow-up
Lead Sponsor:
National Institute of Environmental Health Sciences (NIEHS)
Conditions:
Asthma
Parkinson's Disease
Eligibility:
All Genders
24+ years
Brief Summary
Background: \- The Agricultural Health Study (AHS) is looking at the long-term health effects of farming exposures including pesticides, crops, and animals. The chronic health effects of exposure to ...
Detailed Description
Pesticides are a common environmental exposure due to their widespread use for agricultural, residential, and public health purposes. Farmers and their families represent a unique population for study...
Eligibility Criteria
Inclusion
- INCLUSION AND EXCLUSION CRITERIA:
- All members of the AHS cohort who were eligible for the Phase 3 interview were eligible for the Phase 4 health follow-up. We will apply the same eligibility criteria for future cohort-wide follow-ups. Individuals who only completed the enrollment questionnaire were excluded from Phase 3 eligibility. Depending upon the disease outcome of interest, we may conduct the disease confirmation and validation efforts under this protocol among all participants in the AHS who provided self-reported diagnoses at any interview (e.g. Baseline, or Phases 2-4). For individuals who are unable to participate, we will allow a proxy to provide the information.
- For the validation efforts, individuals who do not confirm their diagnosis of interest (via self or proxy report) will not be asked to provide physician contact for medical records. For specimen collection, we will ask the proxy respondent about whether the individual would be able to provide a sample. In order to obtain MRR we will allow the participant or their medical proxy to sign the form. For cases who are cognitively impaired or deceased, a medical proxy will be identified.
- Determination of cognitive impairment will be made by report of proxy or by interviewer during conversation with participant. Because the AHS enrolled husband - wife pairs, we should be able to identify an appropriate proxy for most participants.
Exclusion
Key Trial Info
Start Date :
July 5 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
89656 Patients enrolled
Trial Details
Trial ID
NCT01399411
Start Date
July 5 2011
Last Update
December 26 2025
Active Locations (3)
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1
University of Iowa
Iowa City, Illinois, United States, 52242
2
NIEHS, Research Triangle Park
Research Triangle Park, North Carolina, United States, 27709
3
Batelle, Inc.
Columbus, Ohio, United States, 43201