Status:
COMPLETED
The Molecular Basis for a Broad Range of Phenotypes Related to hTAS2R38
Lead Sponsor:
Monell Chemical Senses Center
Collaborating Sponsors:
National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions:
Healthy
Eligibility:
All Genders
18-40 years
Brief Summary
This single-site, within-subject, experimental study is designed to test the hypothesis that individuals express taste receptors differently and have different sensitivities to bitter taste samples, w...
Eligibility Criteria
Inclusion
- Key inclusion criteria include age 18-40 years; English speaking, and good health at the time of study participation.
Exclusion
- Key exclusion criteria include cigarette smoking, which alters taste perception, oral disease and subjects undergoing Coumadin therapy. Subjects showing signs of oral disease, including tongue lesions or xerostomia will be excluded from tongue biopsy and therefore excluded from the study. Subjects undergoing Coumadin therapy will be excluded from tongue biopsy due to the risk of bleeding, and therefore excluded from the study. Subjects will not be excluded because of economic status, gender, race or ethnicity.
Key Trial Info
Start Date :
July 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT01399944
Start Date
July 1 2011
End Date
June 1 2013
Last Update
December 18 2017
Active Locations (1)
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1
Monell Chemical Senses Center
Philadelphia, Pennsylvania, United States, 19104