Status:
COMPLETED
The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1
Lead Sponsor:
University of Southern Denmark
Collaborating Sponsors:
Region of Southern Denmark
Conditions:
Pharmacogenetics of Metformin
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The aim of the study is to evaluate the pharmacodynamic impact of metformin in healthy Caucasian volunteers with and without single polymorphisms M420del or R61C in OCT1, thus the study hypothesis is ...
Eligibility Criteria
Inclusion
- Healthy volunteers
- Written consent
- Genotyped in OCT1 for (M420del and R61C)
Exclusion
- Daily medication
- Alcohol abuse
- Pregnancy
- Breastfeeding
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT01400191
Start Date
January 1 2012
End Date
December 1 2012
Last Update
June 26 2015
Active Locations (1)
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1
Clinical pharmacology, Institute og public health, University of Southern Denmark
Odense, Denmark, 5000