Status:

UNKNOWN

Optimal Method of Pain Management in Patients With Multiple Rib Fractures

Lead Sponsor:

Massachusetts General Hospital

Collaborating Sponsors:

I-Flow

Conditions:

3 or More Rib Fractures

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Rib fractures are a common injury of trauma patients and can cause significant pain which, if inadequately treated, can lead to impaired breathing, lung collapse, and respiratory failure. Hence, it is...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Age ≥ 18 years;
  • Three or more rib fractures;
  • Pain
  • Severe pain (i.e. causing deleterious affect on respiratory mechanics, respiratory rate, or oxygen saturations), OR
  • Mild to moderate pain (i.e. minimally affecting respiratory mechanics, respiratory rate, or oxygen saturations) that does not respond to oral or intravenous analgesics within 4 hours;
  • Patient has capacity to provide informed consent, as determined by:
  • Clinical assessment by study staff MD who will explain the study to potential subjects and then ask them to summarize the purpose, procedures, risks and alternatives back to the MD;
  • GCS 15;
  • Clinical assessment by independent MD who will explain the study to potential subjects and then ask them to summarize the purpose, procedures, risks and alternatives back to the MD.
  • Exclusion criteria:
  • Lack capacity to provide informed consent;
  • Intubation at time of enrollment;
  • Contraindications to procedure (e.g. known allergy to local anesthetics).
  • Presence of infection at site of catheter placement;
  • Current use of anticoagulant medication;
  • Known allergy to silver;
  • Inability to obtain informed consent;
  • Body weight \> 300 lbs;
  • Pregnancy;
  • Significant co-morbid medical illness that might alter the metabolism of the anesthetic agents and result in unexpected toxicity (hepatic, renal or cardiopulmonary disease).
  • All women of child-bearing age will receive a urine pregnancy test prior to the start of the interventional portion of the study. A positive test result excludes the patient from inclusion in the study.

Exclusion

    Key Trial Info

    Start Date :

    October 1 2012

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    October 1 2014

    Estimated Enrollment :

    96 Patients enrolled

    Trial Details

    Trial ID

    NCT01401712

    Start Date

    October 1 2012

    End Date

    October 1 2014

    Last Update

    October 29 2013

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Massachusetts General Hospital

    Boston, Massachusetts, United States, 02114