Status:
COMPLETED
Comparison of Markers of Kidney Function
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
Gentian
Conditions:
Chronic Kidney Disease
Renal Insufficiency
Eligibility:
All Genders
1-18 years
Brief Summary
Glomerular filtration rate (GFR) is the best known measurement of kidney function. Serum creatinine (blood test) is the most commonly used marker to predict GFR. It is a convenient, inexpensive test t...
Detailed Description
Study patients will come in for their surveillance biopsy done as standard of care post-transplant. They we be made NPO at midnight prior to the biopsy per routine. On arrival, they will have standard...
Eligibility Criteria
Inclusion
- Renal transplant patient aged 1 to \<19 years old
- Stable allograft function (no history of biopsy proven acute rejection or increase of creatinine of \> 10% from baseline in the past 6 months)
- No changes in maintenance immunosuppression in the month before the protocol biopsy
- Subject and/or parent must be able to understand and provide informed consent
Exclusion
- Biopsy proven acute rejection in the past 6 months
- Change in maintenance immunosuppression in the month before the protocol biopsy
- Known diabetes mellitus
- Known thyroid dysfunction
- Allergy to Iohexol or other contrast media
- Inability or unwillingness of a participant or their legal guardian to give written informed consent or comply with the study protocol
Key Trial Info
Start Date :
August 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT01403766
Start Date
August 1 2011
End Date
December 1 2012
Last Update
November 17 2020
Active Locations (1)
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1
University of California, Los Angeles
Los Angeles, California, United States, 90095