Status:
COMPLETED
A Pilot Study of the Effects of Isotretinoin on Cognition, Learning and Memory
Lead Sponsor:
University of Aberdeen
Conditions:
Acne Vulgaris
Eligibility:
All Genders
16+ years
Phase:
PHASE4
Brief Summary
This prospective study tested the effects of isotretinoin in a cohort of patients receiving standard therapy for acne vulgaris. Subjects completed questionnaires and standardised computer based cognit...
Eligibility Criteria
Inclusion
- Adult subjects age 16 and over with acne vulgaris
- Cases should be candidates for isotretinoin therapy should have severe acne not responding to treatment and at risk of scarring and have discussed the risks, pregnancy prevention program and benefits of this treatment according to normal clinical practise
Exclusion
- Subjects already on treatment with isotretinoin
- Subjects with below normal intelligence who would not understand the CANTAB psychological tests
- Subjects with neurological disease e.g. epilepsy or pre-existing mental health problems
- Pregnant females or females not taking preventive precautions
- Subjects on sedative or psycho-active medications that could interfere with the outcomes tested
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT01404130
Start Date
September 1 2008
End Date
November 1 2010
Last Update
July 27 2011
Active Locations (1)
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1
Anthony Ormerod
Aberdeen, Aberdeenshire, United Kingdom, AB25 2AN