Status:

UNKNOWN

Effects of Tamsulosin 0.4mg on Clinical Outcomes in Korean Men With Severe Symptomatic Benign Prostatic Hyperplasia (BPH)

Lead Sponsor:

Samsung Medical Center

Conditions:

Benign Prostatic Hyperplasia

Eligibility:

MALE

45-80 years

Phase:

NA

Brief Summary

The purpose of this study is to compare the efficacy and safety of tamsulosin 0.4mg (Harnal® D. 0.2mg, 2T) with tamsulosin 0.2mg (Harnal® D 0.2mg, 1T) in patients with severe symptomatic benign prosta...

Eligibility Criteria

Inclusion

  • Severe LUTS : IPSS ≥ 20

Exclusion

  • Post voided residual urine ≥ 150mL
  • Patients performing catheterization
  • Urinary tract infection patients
  • Patients taking 5 alpha reductase inhibitor
  • Known hypersensitivity to tamsulosin
  • History of postural hypotension or syncope
  • Hypertension patients treated with other alpha1-blockers
  • Patients newly taking anticholinergic medication within 1 month
  • Hepatic insufficiency (AST/ALT ≥ 2 times of normal range)
  • Renal insufficiency (s-Cr ≥ 2mg/dL)

Key Trial Info

Start Date :

July 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2013

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT01404637

Start Date

July 1 2011

End Date

October 1 2013

Last Update

August 2 2011

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