Status:

COMPLETED

Effects of High Fruit, Vegetable, and Dairy Intake on Plasma Lipids and Blood Pressure in Healthy Individuals

Lead Sponsor:

UCSF Benioff Children's Hospital Oakland

Collaborating Sponsors:

Dairy Management Inc.

Conditions:

Cardiovascular Disease

Dyslipidemia

Eligibility:

All Genders

22+ years

Phase:

NA

Brief Summary

The Dietary Approaches to Stop Hypertension (DASH) trial has been shown to reduce blood pressure and plasma total and LDL-cholesterol (C) compared to a Western diet, but shows no benefit on other bloo...

Eligibility Criteria

Inclusion

  • Age 22 years and older
  • Average systolic blood pressure \<160 mm Hg and diastolic blood pressure 80 - 95 mm Hg measured on 2 separate days
  • Non-smoking
  • Agrees to abstain from alcohol and dietary supplements during the study
  • Willing to consume all study foods as instructed

Exclusion

  • History of coronary heart disease, cerebrovascular disease, peripheral vascular disease, bleeding disorder, liver or renal disease, diabetes, lung disease, HIV, or cancer (other than skin cancer) in the last 5 years.
  • Taking hormones or drugs known to affect lipid metabolism or blood pressure.
  • Body Mass Index (BMI) \> 35
  • Total- and LDL-cholesterol \> 95th percentile for sex and age.
  • Fasting triglycerides \> 500 mg/dl.
  • Fasting blood sugar (FBS) \> 126 mg/dl.
  • Abnormal thyroid stimulating hormone
  • Not weight stable
  • Pregnant or breast-feeding

Key Trial Info

Start Date :

July 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2013

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT01404897

Start Date

July 1 2011

End Date

December 1 2013

Last Update

March 26 2015

Active Locations (1)

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1

Cholesterol Research Center, Children's Hospital Oakland Research Institute

Berkeley, California, United States, 94705