Status:
COMPLETED
In-Vivo Assessment of Silver Biomaterial Nano-Toxicity 32 Ppm
Lead Sponsor:
University of Utah
Conditions:
Healthy
Eligibility:
All Genders
18-80 years
Phase:
PHASE1
PHASE2
Brief Summary
The investigators propose to study oral commercial silver nanoparticle products on human enzyme activity.
Eligibility Criteria
Inclusion
- 18-80 years old without debilitating chronic disease or history of cardiovascular event.
Exclusion
- Women physically capable of becoming pregnant, who are not using 2 barrier methods of birth control;
- Any female who is nursing;
- History of heavy metal allergy;
- History of asthma or Chronic Obstructive Pulmonary Disease;
- History of renal impairment;
- Symptoms of active upper respiratory disease at time of consent;
- Smoking more than 5 cigarettes or equivalent and not able to stop for 48 hours;
- Ability to discontinue chronic medications or nutraceuticals for 20 days or 5 half-lives of the agent, whichever is longer.
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01405794
Start Date
July 1 2011
End Date
November 1 2011
Last Update
July 4 2016
Active Locations (1)
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1
University of Utah
Salt Lake City, Utah, United States, 84112-5820