Status:
UNKNOWN
Impact of Vitamin A on Gene Expression, in Multiple Sclerosis Patient
Lead Sponsor:
Tehran University of Medical Sciences
Conditions:
Relapsing Remitting Multiple Sclerosis
Eligibility:
All Genders
20-45 years
Phase:
PHASE4
Brief Summary
The aim of this study is the comparison between the effects of supplementation with vitamin A (retinyl palmitate) or placebo for 6 months on gene expression of T CD4+ lymphocyte in multiple sclerotic ...
Detailed Description
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS).The most important reason for the limited success obtained in the treatment and prevention s...
Eligibility Criteria
Inclusion
- Patients who have used interferon beta in last 3 months. Patients with 1-5 EDSS
Exclusion
- Patients who have diseases which affect on Th1/Th2 balance such as asthma, active viral infections, and autoimmune diseases, OR
- Patients who have allergy to vitamin A compounds, OR
- Patients who have used vitamin supplements in last 3 months. -
Key Trial Info
Start Date :
April 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01407211
Start Date
April 1 2011
End Date
September 1 2013
Last Update
July 18 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tehran University of Medical Sciences, School of Public Health
Tehran, Iran