Status:
COMPLETED
Diagnosis and Physiopathology of Insulin Allergy
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Institut National de la Santé Et de la Recherche Médicale, France
URC-CIC Paris Descartes Necker Cochin
Conditions:
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Insulin allergy (IA) is still observed even with recombinant human insulin and insulin analogs. Obviously, the usual attitude facing an allergy, i. e. exclusion of the allergen, poses problems in fac...
Detailed Description
Phenotype of the patient Investigation of allergy per intradermal testing using a wide range of insulin preparations Determination of immunologic and immunogenetic profile particularly CD4 + T cells a...
Eligibility Criteria
Inclusion
- Inclusion criteria :
- Patients aged 18 years old and more with a written informed consent
- Experimental group : type 1 or type 2 diabetic patients with insulin allergy based on clinical criteria
- Active Comparator group: type 1 or type 2 diabetic patients insulin treated without insulin allergy
- Exclusion criteria :
- Not willing participate
- Pregnancy
- Age below 18 years
- Severe Renal failure
- Severe Anaphylactic shock only for the experimental group
- No social security overture
Exclusion
Key Trial Info
Start Date :
February 6 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 27 2016
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT01407640
Start Date
February 6 2012
End Date
July 27 2016
Last Update
September 12 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cochin Hospital
Paris, France, 75005