Status:

COMPLETED

Effect of Beta-Glucan on Cholesterol Lowering

Lead Sponsor:

University of Manitoba

Collaborating Sponsors:

Agriculture and Agri-Food Canada

Conditions:

Hypercholesterolemia

Eligibility:

All Genders

18-78 years

Phase:

NA

Brief Summary

The primary aim of this study is to determine whether the cholesterol-lowering efficacy of barley b- glucan varied as function of molecular weight (MW) and the total daily amount consumed. Our second ...

Detailed Description

This study consists of four dietary phases which are separated by \>28 days wash-out period. During the treatment phase, participants will be provided with all meals for the 35 day period. Breakfast m...

Eligibility Criteria

Inclusion

  • BMI 20-40 kg/m2
  • Fasting cholesterol levels of 5.0-8.0 mmol/L
  • Fasting serum LDL cholesterol levels of 2.7-5.0 mmol/L

Exclusion

  • Pregnant or lactating
  • Taking lipid lowering medication or nutritional supplements that affect blood lipids
  • Dietary restrictions which would affect consuming the study diet for 5-wk for four study phases.
  • Not deemed healthy by study physician

Key Trial Info

Start Date :

November 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2012

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT01408719

Start Date

November 1 2010

End Date

February 1 2012

Last Update

November 5 2015

Active Locations (1)

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Richardson Centre for Functional Foods and Neutraceuticals

Winnipeg, Manitoba, Canada, R3T 2N2