Status:
COMPLETED
Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock.
Lead Sponsor:
University of Roma La Sapienza
Conditions:
Sepsis
Septic Shock
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The purpose of this study is to investigate the effects on systemic hemodynamics, microcirculation and organ function of human Protein C concentrate in patients with sepsis and septic shock.
Detailed Description
Sixty septic patients with plasma protein C activity \< 60 % will be enrolled in the study. Patients will be randomly allocated to be treated with either a) a continuous infusion of human Protein C co...
Eligibility Criteria
Inclusion
- Severe sepsis or septic shock with plasma activity of protein C \< 60 %
Exclusion
- Pregnancy
- Risk of Bleeding
- Hemorragia
- age \< 18
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01411670
Start Date
January 1 2011
End Date
April 1 2015
Last Update
December 2 2015
Active Locations (1)
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1
Departement of Anesthesiology and Intensive Care of the University of Rome La Sapienza
Rome, Italy, 00161