Status:
UNKNOWN
Nickel Desensitization Using Topical Therapy
Lead Sponsor:
University of British Columbia
Conditions:
Allergic Contact Dermatitis
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Nickel contact dermatitis (eczema) is one of the most common allergic conditions affecting the skin. This is a study looking at potentially desensitizing nickel-allergic patients to their allergy usin...
Detailed Description
1. Purpose: To evaluate whether topical anti-inflammatory ointments (calcipotriol, betamethasone dipropionate, or a combination of both) can decrease sensitivity to nickel in known nickel allergic pat...
Eligibility Criteria
Inclusion
- Age \> 18 years.
- Patients have had a diagnosis of nickel allergy determined by patch testing
Exclusion
- Treatment with immunomodulating medications concurrently or in the previous one month
- Active skin disease, particularly to the site of application (forearms)
- Hypersensitivity to calcipotriol, corticosteroids, or vehicle
- Previous anaphylactic reactions to nickel allergen
- Pregnancy or breast-feeding
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2012
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT01413477
Start Date
August 1 2011
End Date
June 1 2012
Last Update
August 10 2011
Active Locations (1)
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1
UBC Contact Dermatitis Clinic
Vancouver, British Columbia, Canada, V5Z 3Y1