Status:
TERMINATED
Calcineurin Activity in Renal Recipients
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Renal Transplant Rejection
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose is to define if calcineurin activity is a better biological parameter than blood concentration for the therapeutic tacrolimus monitoring.
Detailed Description
Some authors showed that the determination of calcineurin (enzyme of cyclosporin and tacrolimus action) activity was very interesting in bone narrow and hepatic transplant in order to monitor tacrolim...
Eligibility Criteria
Inclusion
- adult renal transplant recipients
- treated by tacrolimus (Prograf or ADVAGRAF), corticoids, Cellcept,
Exclusion
- patients with a high risk of bad compliance (toxicomania, severe psychiatric troubles)
- multiorgan transplant patients with mTOR inhibitors treatments
- HIV infected patients
- lack of consent for this study
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2010
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT01413685
Start Date
January 1 2009
End Date
July 1 2010
Last Update
November 14 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hôpital Henri Mondor
Créteil, France, 94000