Status:
COMPLETED
The Effects of Isotonic and Hypertonic Saline Infusion on Renal Biomarkers in Healthy Young Subjects
Lead Sponsor:
Regional Hospital Holstebro
Conditions:
Nephropathy
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The kidneys have numerous salt and water channels and play a major role in the regulation of sodium and water. We do not know how these channels work in certain water and sodium accumulating medical c...
Detailed Description
25 healthy subjects from age 18-45 are recruited. Subjects will be examined on three examination days. Four days prior to the examination days the subjects will consume a standard diet based on the a...
Eligibility Criteria
Inclusion
- healthy males and females
- age 18-45
- BMI range 18,5-30,0 kg/m2
Exclusion
- hypertension (ie ambulatory BP \>130 mmHg systolic or/and \>80 mmHg diastolic)
- history or clinical significant signs of heart, lung, liver, kidney, endocrine, brain or neoplastic disease.
- alcohol abuse
- drug abuse
- smoking
- pregnancy or nursing
- blood donation within a month prior to examination
- Medical treatment apart from oral contraception
Key Trial Info
Start Date :
April 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT01414088
Start Date
April 1 2011
End Date
April 1 2012
Last Update
May 20 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Medicinsk Forskning, Regionshospitalet i Holstebro
Holstebro, Denmark, 7500