Status:
UNKNOWN
ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia
Lead Sponsor:
Maisonneuve-Rosemont Hospital
Collaborating Sponsors:
Université de Montréal
Conditions:
Obstetric Anesthesia
Spinal Anesthesia
Eligibility:
FEMALE
Phase:
PHASE4
Brief Summary
The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a ces...
Detailed Description
The incidence of spinal anesthesia-induced hypotension in pregnant women undergoing a cesarean section is high. A preoperative fluid bolus of undetermined volume is frequently administered to lower th...
Eligibility Criteria
Inclusion
- Healthy pregnant women (ASA I or II)
- Normal pregnancy
- Term gestation (37 weeks and above)
- Elective cesarean section
- Spinal anesthesia
Exclusion
- Cardiopathies
- Hypertensive disease/ pre-eclampsia / eclampsia
- Any contraindication to neuraxial anesthesia
- Patient refusal
- Body mass index \> 30 at first antenatal visit and \> 32 at cesarean section
- Twin pregnancy
- Known allergies to HES
- Emergency cesarean section
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01415284
Start Date
October 1 2011
End Date
June 1 2013
Last Update
February 15 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Maisonneuve-Rosemont Hospital
Montreal, Quebec, Canada, H1T 2M4