Status:
COMPLETED
Effect of Ischemic Strokes on Recovery From Intracerebral Hemorrhages
Lead Sponsor:
Rush University Medical Center
Collaborating Sponsors:
American Heart Association
Rush University
Conditions:
Hemorrhage; Intracerebral, Nontraumatic
Ischemic Strokes
Eligibility:
All Genders
19-79 years
Brief Summary
Intracerebral hemorrhage (ICH) occurs when small arteries in the brain rupture due to weakening by age, high blood pressure, and/or elevated cholesterol. In addition to artery rupture, recent data sug...
Detailed Description
Diffusion weighted imaging (DWI) is a sensitive method to assess for secondary ischemia in patients with acute brain injury. By comparing the outcomes of patients with and without DWI abnormalities, w...
Eligibility Criteria
Inclusion
- Patients \> 18 years and \< 80 years
- Spontaneous intracerebral hemorrhage documented by CT scan
- Less than 24 hours from time last seen normal to first medical evaluation
- No prior clinical history of stroke (i.e. subarachnoid hemorrhage, ICH, or ischemic strokes)
Exclusion
- Pregnancy
- History of cancer
- Pre-admission mRS \> 2
- Glasgow Coma Scale less than 5
- ICH secondary to aneurysm, vascular malformation, mycotic aneurysm, primary or metastatic tumor, trauma, warfarin-related ICH, acute-fibrinolytic associated ICH, or coagulopathy
- Associated epidural or subdural hematoma
- Surgical intervention \< 48 hours from admission
- Hemodynamic instability (need for vasopressor therapy)
- Acute hypoxemic or hypercapnic respiratory failure
- History of deep venous thrombosis
- Contraindications to MRI based upon institutional safety checklist
Key Trial Info
Start Date :
September 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2017
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT01417117
Start Date
September 1 2011
End Date
June 1 2017
Last Update
October 20 2017
Active Locations (1)
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1
Rush University Medical Center
Chicago, Illinois, United States, 60612