Status:
COMPLETED
Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery
Lead Sponsor:
Oxford University Hospitals NHS Trust
Conditions:
Oral Cancer
Head and Neck Cancer
Eligibility:
All Genders
17+ years
Phase:
PHASE4
Brief Summary
Following surgery to remove tumours of the head and neck, patients undergo reconstruction with free flaps - tissue that is taken from elsewhere in the body and given a new blood supply by attaching it...
Detailed Description
The optimal sympathomimetic drug to support blood pressure without adverse vasoconstriction of free flap circulation remains unknown. This study examined the effects of four agents (epinephrine, norep...
Eligibility Criteria
Inclusion
- Patients undergoing free tissue transfer surgery at the John Radcliffe Hospital wih planned post-operative admission to the intensive care unit.
Exclusion
- Pregnancy
- Weight \>100kg
- Contraindications to pressor infusions
- Overnight ventilation not indicated
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01418118
Start Date
October 1 2008
End Date
February 1 2010
Last Update
August 16 2011
Active Locations (1)
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1
John Radcliffe Hospital
Oxford, Oxfordshire, United Kingdom, OX3 9DU