Status:
COMPLETED
Non-Invasive Imaging of Atherosclerosis
Lead Sponsor:
Icahn School of Medicine at Mount Sinai
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)
Conditions:
Atherosclerosis
Eligibility:
All Genders
20+ years
Brief Summary
The purpose of this study is to develop and validate novel magnetic resonance imaging (MRI), dynamic contrast enhanced (DCE)-MRI and positron emission tomography (PET)/MR techniques for the detection ...
Detailed Description
Atherosclerosis is responsible for the majority of disabilities and deaths in developed countries. Previous studies have shown that sudden clinical events correlate highly with plaque composition and ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Volunteers with carotid artery disease who are MRI and CT compatible.
- All subjects will have either a
- clinical diagnosis of atherosclerosis,
- and/or risk factors
- and/or family history of disease
- Exclusion criteria:
- Glomerular filtration rate \<30mg/ml (for MRI with contrast)
- Subjects who have any ferromagnetic implants (e.g. aneurysm clip, ICD, pacemaker, etc.) or a condition that may be contraindicated for the MRI procedure (e.g. claustrophobia )
- Pregnant patients will be excluded from the present study.
Exclusion
Key Trial Info
Start Date :
September 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 9 2020
Estimated Enrollment :
886 Patients enrolled
Trial Details
Trial ID
NCT01418313
Start Date
September 1 2011
End Date
March 9 2020
Last Update
August 3 2020
Active Locations (1)
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1
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029