Status:
UNKNOWN
The Metabolic Effects of Antidepressants in Patients Diagnosed With Major Depressive Disorder
Lead Sponsor:
Ziv Hospital
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
18-65 years
Brief Summary
Objective There is growing evidence showing a relation between depression, metabolic syndrome, diabetes, cardiovascular disease (1), serum lipid profile (2,3) and body weight (4), as well as the effec...
Eligibility Criteria
Inclusion
- MDD diagnosed patients with a Hamilton Depression Rating Scale (HDRS) score of at least 18 points. Patients not treated with medications or such that had shown resistance to treatment, and were therefore assigned for drug replacement.
- Patients on stable therapy for hypertension, diabetes mellitus, hypothyroidism, dyslipidemia and / or weight lowering medications
Exclusion
- Patients receiving antipsychotic treatment as well as patients on mood stabilizers will be excluded.
- Patients with uncontrolled diabetes mellitus, uncontrolled thyroid functioning, or uncontrolled hypertension, as well as patients who regularly consume alcohol will be excluded.
- Patients with uncontrolled malignancy are excluded as well.
Key Trial Info
Start Date :
May 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01418638
Start Date
May 1 2012
Last Update
February 20 2013
Active Locations (1)
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1
Ziv MC
Safed, Israel, 13110