Status:
UNKNOWN
Role of Sildenafil Citrate in Patients With Unexplained Recurrent Miscarriages
Lead Sponsor:
Ain Shams University
Conditions:
Recurrent Miscarriage
Eligibility:
FEMALE
18-35 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether sildenafil citrate is effective in improving uterine artery blood flow and oxidative stress in patients with unexplained recurrent miscarriages
Eligibility Criteria
Inclusion
- Age 18-35 years
- Three or more recurrent miscarriages before the 24th week of gestation with no apparent cause for their previous losses
- Three or more months have elapsed since the last abortion
- Postmenstrual period
- No other therapy allowed during our treatment course
Exclusion
- Concomitant use of organic nitrites, or nitrates
- Severe hepatic, renal, or cardiovascular impairment
- History of stroke or myocardial infarction
- Patients with retinitis pigmentosa.
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2012
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT01419392
Start Date
September 1 2011
End Date
June 1 2012
Last Update
April 17 2012
Active Locations (1)
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1
Ain Shams University Maternity Hospital, Obstetrics and Gynecology Department
Cairo, Cairo Governorate, Egypt