Status:
UNKNOWN
Association Between Urine Concentration Ability and the Progression of Chronic Kidney Disease
Lead Sponsor:
Benaya Rozen-Zvi
Conditions:
Chronic Kidney Disease
Eligibility:
All Genders
18+ years
Brief Summary
The study hypothesis is that urine concentrating ability can predict the rate of kidney function decline. Patients with kidney disease at the investigatorsclinic will be asked to give first morning u...
Detailed Description
Design: Prospective observational study Setting: Predialysis clinic. Participants: We will include adults \>18 years providing signed informed consent. Inclusion: Patients with CKD and estimate...
Eligibility Criteria
Inclusion
- Patients with CKD and estimated GFR of less then 50 mL per minute estimated by the short MDRD equation base on two creatinine values taken at least two weeks apart and are not getting steroids or immunosuppressive medication as treatment for their primary kidney disease.
Exclusion
- Life expectancy of less then 6 month.
- Expected to start renal replacement therapy within 3 month.
- Acute or acute on chronic renal failure with reversible component.
- Treatment with AVP inhibitors.
- Chronic hyponatremia (Na+\<135 in two measurement two weeks apart).
- Primary polydipsia.
- Inability to give informed consent.
- Clinical hypovolemia.
Key Trial Info
Start Date :
October 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2013
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01423045
Start Date
October 1 2011
End Date
October 1 2013
Last Update
August 25 2011
Active Locations (1)
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1
Pre dialysis clinic Dan Petach Tiqua county General health service
Ganey Tiqua, Israel, 55900