Status:
UNKNOWN
Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia
Lead Sponsor:
St. Anna Kinderkrebsforschung
Collaborating Sponsors:
International BFM Study Group
Conditions:
Lymphoblastic Leukemia, Acute, Childhood;
Eligibility:
All Genders
3-18 years
Phase:
PHASE3
Brief Summary
With this protocol the ALL-SZT BFM international study group wants to evaluate whether hematopoietic stem cell transplantation (HSCT) from matched family or unrelated matched donors (MD) is equivalen...
Detailed Description
Patients with high risk or relapsed acute lymphoblastic leukaemia (ALL) have a worse prognosis compared to all other patients with ALL. For these patients additional therapy approaches are required af...
Eligibility Criteria
Inclusion
- age at time of initial diagnosis or relapse diagnosis, respectively under or equal 18 years
- indication for allogeneic hematopoietic stem cell transplantation (HSCT)
- complete remission before hematopoietic stem cell transplantation (HSCT)
- written consent of the parents (legal guardian) and, if necessary, the minor patient via Informed Consent Form
- no pregnancy
- no secondary malignancy
- no previous hematopoietic stem cell transplantation (HSCT)
- hematopoietic stem cell transplantation (HSCT) is performed in a study participating centre.
Exclusion
- age at time of initial diagnosis or relapse diagnosis, respectively above 18 years
- no indication for allogeneic HSCT
- no complete remission before SCT
- no written consent of the parents (legal guardian) and, if necessary, the minor patient via Informed Consent Form
- pregnancy
- secondary malignancy
- previous HSCT
- HSCT is not performed in a study participating centre.
Key Trial Info
Start Date :
July 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2016
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT01423747
Start Date
July 1 2003
End Date
September 1 2016
Last Update
June 26 2015
Active Locations (24)
Enter a location and click search to find clinical trials sorted by distance.
1
Universitätsklinik für Kinder- und Jugendheilkunde, Klin. Abt. f. Hämato-Onkologie
Graz, Austria, 8036
2
Universitätsklinik für Kinder- und Jugendheilkunde
Innsbruck, Austria, 6020
3
St. Anna Kinderspital
Vienna, Austria, 1090
4
Charité Campus Virchow- Klinikum, Klinikum der Pädiatrie, Onkologie/Hämatologie/KMT
Berlin, Germany, 13353