Status:
COMPLETED
Effects of Mechanical Insufflation-Exsufflation in Preventing Respiratory Failure After Extubation
Lead Sponsor:
Hospital Sao Joao
Conditions:
Post-extubation Failure
Persistent Weaning Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Weaning protocols that include the use of noninvasive ventilation (NIV), decreases the incidence of re-intubation and ICU length of stay. However, the role of NIV in post-extubation failure is still n...
Detailed Description
Patients under mechanical ventilation (MV) for more than 48 hours with specific inclusion criteria, who successfully tolerated an spontaneous breathing trial (SBT) were randomly allocated before extub...
Eligibility Criteria
Inclusion
- Patients older than 18 years and under mechanical ventilation, for more than 48 hours, for acute hypoxemic and/or hypercapnic respiratory failure from a specific etiology
Exclusion
- facial or cranial trauma, tracheostomy, active upper gastrointestinal bleeding, neurologic instability (inability to respond to direct simple orders), hemodynamic instability, lack of cooperation and confirmed diagnosis of neuromuscular disease.
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT01424202
Start Date
September 1 2008
End Date
October 1 2010
Last Update
August 26 2011
Active Locations (1)
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1
Intensive Care and Emergency Department;, Faculty of Medicine, University Hospital of S. João
Porto, Porto District, Portugal, 4200-319