Status:

COMPLETED

Fluorescent Evaluation of Colorectal Anastamoses

Lead Sponsor:

Maimonides Medical Center

Conditions:

Rectal Neoplasms

Colon Neoplasms

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

Bowel removal is indicated for various types of colon and rectal disease, including colon cancer, rectal cancer, diverticulitis, and inflammatory bowel disease among others. Following removal of the ...

Detailed Description

The purpose of this study is to evaluate whether systemically injected ICG, when fluorescing in response to NIR illumination, can assist with the assessment of perfusion at a bowel anastomotic site. T...

Eligibility Criteria

Inclusion

  • Candidates for this study must meet ALL of the following inclusion criteria:
  • Subject is willing and able to provide an informed consent
  • Subject is willing and able to comply with the study procedures
  • Subject speaks English and is able to understand the study procedures
  • A pregnancy test for women of childbearing potential prior to surgery
  • Subject is scheduled for laparoscopic low anterior resection

Exclusion

  • Candidates for this study who meet any of the following criteria at the time of the baseline visit are NOT eligible to be enrolled in this study:
  • Subject has uremia, serum creatinine \>2.5 mg/dl
  • Subject has a previous history of adverse reaction or allergy to ICG, iodine, shellfish or iodine dyes
  • Subjects in whom the use of x-ray dye or ICG is contraindicated including development of adverse events when previously or presently administered
  • Subject has any medical condition, which in the judgment of the Investigator and/or designee makes the subject a poor candidate for the investigational procedure
  • Subject is a pregnant or lactating female
  • Subject is actively participating in another drug, biologic and/or device protocol

Key Trial Info

Start Date :

May 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2016

Estimated Enrollment :

7 Patients enrolled

Trial Details

Trial ID

NCT01424293

Start Date

May 1 2010

End Date

September 1 2016

Last Update

July 13 2021

Active Locations (1)

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Maimonides Medical Center

Brooklyn, New York, United States, 11219