Status:
UNKNOWN
Adjuvanted Influenza Vaccine Effectiveness in the Elderly (65+Yrs)
Lead Sponsor:
Fraser Health
Collaborating Sponsors:
Novartis Pharmaceuticals
Conditions:
Influenza
Eligibility:
All Genders
65+ years
Brief Summary
This study explores the hypothesis that the use of an adjuvanted influenza vaccine in the elderly will produce greater vaccine effectiveness in their group.
Detailed Description
To evaluate the effectiveness of adjuvanted trivalent inactivated influenza vaccine in the elderly (aged ≥ 65 years) through the reduction in relative risk of microbiologically confirmed influenza ill...
Eligibility Criteria
Inclusion
- Elderly tested for influenza as part of routine clinical care in the Lower Mainland and on Vancouver Island during the influenza season.
- Cases: Proven influenza diagnosed on naso-pharyngeal swab via PCR Controls: Elderly with influenza-like-illness testing negative for influenza during the influenza season.
Exclusion
- Known immunodeficiency disorders (including HIV)
- Current or recent (within 90 days prior to first dose of influenza vaccine) immunosuppressive treatment including chronic oral steroids (1mg/kg for \> 4 weeks), cytotoxic chemotherapy, radiation therapy, other immunosuppressive drug and biologic agents Note: Use of topical or inhalant corticosteroids is acceptable.
- Administration of immunoglobulins during the study period;
Key Trial Info
Start Date :
November 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2013
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT01424371
Start Date
November 1 2011
End Date
June 1 2013
Last Update
October 1 2012
Active Locations (1)
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1
Fraser Health Authority
Surrey, British Columbia, Canada, V3T 5H5