Status:

TERMINATED

ST Monitoring to Detect Acute Coronary Syndrome Events in Implantable Cardioverter Defibrillator Patients

Lead Sponsor:

Abbott Medical Devices

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This is a prospective, non-randomized, multicenter, pivotal Investigational Device Exemption (IDE) study. The intent of this study is to demonstrate the safety and effectiveness of the ST Monitoring F...

Detailed Description

This is a prospective, non-randomized, multicenter, pivotal IDE study. The intent of this study is to demonstrate the safety and effectiveness of the ST Monitoring Feature in the Fortify® ST, Fortify ...

Eligibility Criteria

Inclusion

  • Eligible patients will meet all of the following:
  • Have an indication for an ICD implantation or pulse generator change
  • Have documented coronary artery disease. Documented coronary artery disease is defined as having at least one of the following present a) evidence of a prior MI on ECG and/or cardiac enzymes, b) prior revascularization (by coronary artery bypass grafting or percutaneous coronary intervention) c) angina and/or ST-T wave abnormalities indicative of ischemia on exercise stress test, nuclear stress test, or echo stress test, or d) coronary artery disease diagnosed by coronary angiography.
  • Willing and able to comply with protocol requirements, including keeping all required visits
  • Willing to participate in the study and able to sign an IRB approved informed consent form
  • Be at least 18 years of age when enrolled in the study

Exclusion

  • Patients will be excluded if they meet any of the following:
  • Are pacemaker dependent (defined as a need for ventricular pacing ≥ 20% of the time)
  • Have NYHA Class IV Heart Failure
  • Have persistent or permanent atrial fibrillation
  • Have a known history of intermittent Bundle Branch Block
  • Pregnant or planning a pregnancy during the study participation
  • Have a life expectancy of \< 1 year due to any condition
  • Are currently participating in a clinical investigation that includes an active treatment arm.

Key Trial Info

Start Date :

August 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2017

Estimated Enrollment :

2258 Patients enrolled

Trial Details

Trial ID

NCT01424722

Start Date

August 1 2011

End Date

June 1 2017

Last Update

January 28 2021

Active Locations (97)

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Page 1 of 25 (97 locations)

1

Cardiovascular Associates PC

Birmingham, Alabama, United States, 35209

2

Cardiovascular Associates PC

Birmingham, Alabama, United States, 35213

3

University Hospital - Univ. of Alabama at Birmingham (UAB)

Birmingham, Alabama, United States, 35233

4

Heart Center Research, LLC

Huntsville, Alabama, United States, 35801