Status:
COMPLETED
Neural Oscillations as Genetic and Functional Biomarkers in Normal and Disease States
Lead Sponsor:
University of Maryland, Baltimore
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Schizophrenia
Schizoaffective Disorder
Eligibility:
All Genders
14-62 years
Brief Summary
The principle aim of the project is to analyze brain electrical activity and genetic information that will help identify the nature and cause of the disease schizophrenia. This effort should lay the g...
Detailed Description
There are several studies and hypotheses to be tested. This project includes a cross-sectional study design measuring brain waves, clinical symptoms, cognitive and functional ability, and genetic info...
Eligibility Criteria
Inclusion
- Male and Female between ages 14-62 (clinical assessment and blood draw only above 62)
- Ability to give written assent (subjects who are below the age of 18)
- Ability to give written informed consent (age 18 or above)
- Sufficient understanding of the study and risks (ESC score 10 or above)
- Subjects above age 62 will not participate in brain electrical activity measurements although they may still participate in clinical assessments and blood draw.
Exclusion
- Inability to sign informed consent/assent
- Any major medical illness that may affect normal brain functioning. Examples of these conditions include, but not limited to, stroke, repeated seizure, history of significant head trauma, CNS infection or tumor, an other significant brain neurological conditions.
- Significant alcohol or drug use (substance dependence within 6 months or substance abuse within 1 month) other than nicotine or marijuana dependence.
- Woman who is pregnant (child bearing potential but not on contraceptive and missing menstrual period; or by self-report; or by positive pregnancy test).
- Can not refrain from using alcohol and/or marijuana 24 hours or more\& cigarette smoking half and hour or more prior to experiments.
Key Trial Info
Start Date :
November 30 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2024
Estimated Enrollment :
800 Patients enrolled
Trial Details
Trial ID
NCT01425671
Start Date
November 30 2010
End Date
January 1 2024
Last Update
April 26 2024
Active Locations (1)
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1
Maryland Psychiatric Research Center
Baltimore, Maryland, United States, 21228