Status:
UNKNOWN
Pilot Project of Adaptive Thoracic Radiotherapy for Small Cell Lung Cancer
Lead Sponsor:
AHS Cancer Control Alberta
Conditions:
Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
This study is intended to assess the feasibility of adjusting a radiation plan during its course to accommodate for a shrinking tumor target. The investigators hypothesize that an adaptive radiotherap...
Eligibility Criteria
Inclusion
- patients with histologically or cytologically proven newly diagnosed small cell lung cancer
- chest-confined disease (including bulky intrathoracic disease)
- adequate pulmonary function tests (FEV-1\>1.0 L, DLCO\>50%)
- patients of childbearing potential must practice adequate contraception
- Age \> or = 18 years
- Karnofsky performance status \> or = 70
- eligible for concurrent chemoradiotherapy
Exclusion
- patients who have undergone complete or subtotal tumour resection
- evidence of non-small cell histology
- prior or concurrent malignancy except non-melanomatous skin cancer unless disease-free for at least 5 years
- prior RT to the thorax or neck
- compromised lung function with inadequate pulmonary function tests (FEV-1\<1.0,DLCO\<50%)
- pregnant women
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01426841
Start Date
August 1 2011
End Date
April 1 2015
Last Update
October 2 2014
Active Locations (1)
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1
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2