Status:

ENROLLING_BY_INVITATION

Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)

Lead Sponsor:

Mayo Clinic

Conditions:

Spontaneous Coronary Artery Dissection

SCAD

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels tha...

Detailed Description

Study question: Do mutations within certain genes cause or confer susceptibility to spontaneous coronary artery dissection (SCAD)? Specific aims: 1. Create a genomic DNA and plasma biobank for indiv...

Eligibility Criteria

Inclusion

  • Men and women able to give informed consent and complete a 2 page questionnaire
  • Diagnosis of one or more episodes of spontaneous coronary artery dissection (SCAD)
  • Biological parent of individual with SCAD
  • Relative with fibromuscular dysplasia, arterial aneurysm, or arterial dissection

Exclusion

  • Lack of confirmation of SCAD diagnosis

Key Trial Info

Start Date :

May 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2030

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT01427179

Start Date

May 1 2011

End Date

December 1 2030

Last Update

March 26 2025

Active Locations (1)

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1

Mayo Clinic

Rochester, Minnesota, United States, 55905