Status:
COMPLETED
AIMS Study: Improving HIV Treatment Adherence
Lead Sponsor:
Wageningen University
Collaborating Sponsors:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
ZonMw: The Netherlands Organisation for Health Research and Development
Conditions:
HIV
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The objectives of the main study are to evaluate the effectiveness and the cost-effectiveness of a counseling intervention to support medication intake among patients treated for HIV. The aim is that ...
Detailed Description
\*\*MAIN STUDY\*\* BACKGROUND: Adherence to HIV-medication is an important predictor of treatment success, yet between 25-40% of the patients does not always take the medication as prescribed. A nurs...
Eligibility Criteria
Inclusion
- Inclusion Criteria treatment-naive patients initiating cART:
- \- All patients are eligible
- Inclusion criteria treatment experienced patients:
- Started cART after 1996, and
- Have been on cART for at least 9 months, and
- Had at least one detectable viral load (including blips) during the last 3 years (counting of these 3 years starts after the first 9 months on cART), and
- Had suboptimal adherence (\<95% BID, \<100% QD) during 2 months baseline measurement.
- Exclusion criteria for treatment-naive and experienced patients:
- Age \<18 years
- Psychiatric disorders or other comorbidities precluding compliance with study procedures
- Pregnancy
- Plans to interrupt treatment in the next 14 months
- Life expectancy less than one year as determined by physician
- Not able to communicate in English or Dutch
- HIV resistant to three or more of the currently available antiretroviral drug classes
- About to initiate intensive hepatitis C treatment
Exclusion
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2015
Estimated Enrollment :
226 Patients enrolled
Trial Details
Trial ID
NCT01429142
Start Date
September 1 2011
End Date
May 1 2015
Last Update
November 15 2016
Active Locations (7)
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1
Erasmus Medical Center
Rotterdam, South Holland, Netherlands, 3000 CA
2
Sint Lucas Andreas Ziekenhuis
Amsterdam, Netherlands, 1006 AE
3
Slotervaartziekenhuis
Amsterdam, Netherlands, 1066 EC
4
Academic Medical Center
Amsterdam, Netherlands, 1105AZ