Status:

COMPLETED

Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis

Lead Sponsor:

Mahidol University

Conditions:

Chronic Sinusitis

Eligibility:

All Genders

Brief Summary

The propose of this study to determine efficacy and complication of gentamicin nasal irrigation in chronic rhinosinusitis

Detailed Description

Chronic rhinosinusitis (CRS) is characterized by symptoms \> 12 weeks Two or more symptoms one of which should be either nasal blockage /obstruction/congestion or nasal discharge (anterior/posterior ...

Eligibility Criteria

Inclusion

  • Chronic rhinosinusitis patients who were followed in pediatrics allergy clinic at Siriraj hospital between January 1, 2005, and February 28, 2011
  • Gentamicin nasal irrigation usage for longer than 3 months

Exclusion

  • Patients who used azithromycin prophylaxis within 1 year before and 6 months after started gentamicin nasal irrigation
  • Patients received IVIG within 1 year before and 6 months after started gentamicin nasal irrigation
  • Patients underwent endoscopic sinus surgery within 1 year before and 6 months after started gentamicin nasal irrigation
  • Patients received IT within 1 year before and 6 months after started gentamicin nasal irrigation

Key Trial Info

Start Date :

March 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2012

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01430026

Start Date

March 1 2011

End Date

March 1 2012

Last Update

September 18 2015

Active Locations (1)

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1

Faculty of Medicine Siriraj Hospital

Bangkoknoi, Bangkok, Thailand, 10700